What is the suggested dosage of alprazolam to alleviate fear, anxiety, or stress in horses before an event?

The pharmacological management of fear, anxiety, or stress in horses often includes the use of benzodiazepines, such as alprazolam. The suggested dosage of 0.04-0.1 mg/kg orally is commonly recommended for alleviating mild to moderate anxiety in horses, particularly in situations that could provoke fear, such as transport, competitions, or veterinary procedures. This dosage range allows for effective sedation without excessive respiratory depression or excessive sedation, which can impede the horse's performance or ability to respond to instructions.

Utilizing this lower dosage helps to ensure that the horse remains calm yet functional, which is vital in environments where alertness may still be required. Higher dosages could lead to over-sedation, loss of coordination, or adverse effects, which is why it's essential to stay within the recommended range for optimal safety and efficacy in managing anxiety.